HILLTOP CHIHUAHUAS & BOXERS

Your Dog's Home Before Home

Flicker

NCSU, COLLEGE OF VETERINARY MEDICINE
CARDIAC GENETICS LABORATORY
http://www.cvm.ncsu.edu/vhc/csds/vegl/indes.html
R462A 1060 William Moore Drive
RALEIGH,NC  27607
Phone: 9195138279      Fax: 

Owner: 




Veterinarian:




HILLTOP

UNION BRIDGE, MD 21791

DR. 
HILLTOP KENNEL
238 CLEAR RIDGE ROAD
UNION BRIDGE, MD 21791
Phone4435367441   
Fax
Accession Number: CG12-00038

Received: 01/06/2012   Reported: 01/13/2012 
Species: CANINE
Breed: BOXER
Sex: F   Age: 3Y9M
Animal ID: FLICKER
Case Ref#: 
Specimen: SWB

Results:
GENETIC INFO   ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY (ARVC) IS A FAIRLY COMMON FORM OF HEART DISEASE IN THE BOXER DOG. IT IS INHERITED AND OUR LABORATORY HAS IDENTIFIED A MUTATION RESPONSIBLE FOR THE GENE IN SOME BOXERS. HOWEVER, IT SHOULD BE NOTED THAT IN HUMAN BEINGS WITH THE SAME DISEASE, THERE ARE MANY DIFFERENT GENETIC MUTATIONS WHICH CAN CAUSE THIS DISEASE. WE DO NOT YET KNOW IF THIS IS THE ONLY MUTATION IN THE BOXER OR IF THERE WILL BE MANY DIFFERENT MUTATIONS. PLEASE KEEP IN MIND THAT WE ARE CONTINUALLY LEARNING ABOUT THIS DISEASE AND RECOMMENDATIONS WILL BE ALTERED AS WE OBTAIN MORE INFORMATION. 
CURRENTLY OUR INTERPRETATION OF THE TEST IS: 
NEGATIVE RESULTS: 
THE ABSENCE OF THE MUTATION IN THIS DOG, DOES NOT MEAN THAT IT WILL NEVER DEVELOP THE DISEASE. IT MEANS THAT IT DOES NOT HAVE THE ONLY KNOWN MUTATION THAT CAN CAUSE THE DISEASE IN THE DOG AT THIS TIME. 
POSITIVE RESULTS: 
DOGS THAT ARE POSITIVE FOR THE TEST WILL NOT NECESSARILY DEVELOP SIGNIFICANT HEART DISEASE AND DIE FROM THE DISEASE. SOME DOGS WILL DEVELOP A VERY MILD FORM OF THE DISEASE AND WILL LIVE QUITE COMFORTABLY, SOME MAY NEED TREATMENT. 
IMPORTANTLY, BREEDING DECISIONS SHOULD BE MADE CAREFULLY. AT THIS TIME WE HAVE DO NOT YET KNOW WHAT PERCENTAGE OF BOXERS WILL BE POSITIVE FOR THE MUTATION. HOWEVER, REMOVAL OF A SIGNIFICANT NUMBER OF DOGS FROM THE BREEDING POPULATION COULD BE VERY BAD FOR THE BOXER DOG BREED. REMEMBER THAT DOGS THAT CARRY THIS MUTATION ALSO CARRY OTHER IMPORTANT GOOD GENES THAT WE DO NOT WANT TO LOSE FROM THE BREED.
BOXER ARVC   Negative

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Jazzy

NCSU, COLLEGE OF VETERINARY MEDICINE
CARDIAC GENETICS LABORATORY
http://www.cvm.ncsu.edu/vhc/csds/vegl/indes.html
R462A 1060 William Moore Drive
RALEIGH,NC  27607
Phone: 9195138279      Fax: 

Owner: 




Veterinarian:




HILLTOP

UNION BRIDGE, MD 21791

DR. 
HILLTOP KENNEL
238 CLEAR RIDGE ROAD
UNION BRIDGE, MD 21791
Phone4435367441   
Fax
Accession Number: CG12-00241

Received: 02/06/2012   Reported: 02/10/2012 
Species: CANINE
Breed: BOXER
Sex: F   Age: 3Y10M
Animal ID: JAZZY
Case Ref#: 
Specimen: SWB

Results:
GENETIC INFO   ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY (ARVC) IS A FAIRLY COMMON FORM OF HEART DISEASE IN THE BOXER DOG. IT IS INHERITED AND OUR LABORATORY HAS IDENTIFIED A MUTATION RESPONSIBLE FOR THE GENE IN SOME BOXERS. HOWEVER, IT SHOULD BE NOTED THAT IN HUMAN BEINGS WITH THE SAME DISEASE, THERE ARE MANY DIFFERENT GENETIC MUTATIONS WHICH CAN CAUSE THIS DISEASE. WE DO NOT YET KNOW IF THIS IS THE ONLY MUTATION IN THE BOXER OR IF THERE WILL BE MANY DIFFERENT MUTATIONS. PLEASE KEEP IN MIND THAT WE ARE CONTINUALLY LEARNING ABOUT THIS DISEASE AND RECOMMENDATIONS WILL BE ALTERED AS WE OBTAIN MORE INFORMATION. 
CURRENTLY OUR INTERPRETATION OF THE TEST IS: 
NEGATIVE RESULTS: 
THE ABSENCE OF THE MUTATION IN THIS DOG, DOES NOT MEAN THAT IT WILL NEVER DEVELOP THE DISEASE. IT MEANS THAT IT DOES NOT HAVE THE ONLY KNOWN MUTATION THAT CAN CAUSE THE DISEASE IN THE DOG AT THIS TIME. 
POSITIVE RESULTS: 
DOGS THAT ARE POSITIVE FOR THE TEST WILL NOT NECESSARILY DEVELOP SIGNIFICANT HEART DISEASE AND DIE FROM THE DISEASE. SOME DOGS WILL DEVELOP A VERY MILD FORM OF THE DISEASE AND WILL LIVE QUITE COMFORTABLY, SOME MAY NEED TREATMENT. 
IMPORTANTLY, BREEDING DECISIONS SHOULD BE MADE CAREFULLY. AT THIS TIME WE HAVE DO NOT YET KNOW WHAT PERCENTAGE OF BOXERS WILL BE POSITIVE FOR THE MUTATION. HOWEVER, REMOVAL OF A SIGNIFICANT NUMBER OF DOGS FROM THE BREEDING POPULATION COULD BE VERY BAD FOR THE BOXER DOG BREED. REMEMBER THAT DOGS THAT CARRY THIS MUTATION ALSO CARRY OTHER IMPORTANT GOOD GENES THAT WE DO NOT WANT TO LOSE FROM THE BREED.
BOXER ARVC   Negative

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Oppie

NCSU, COLLEGE OF VETERINARY MEDICINE
CARDIAC GENETICS LABORATORY
http://www.cvm.ncsu.edu/vhc/csds/vegl/indes.html
R462A 1060 William Moore Drive
RALEIGH,NC  27607
Phone: 9195138279      Fax: 

Owner: 





Veterinarian:






SARA RUSSELL
11150 BENNIE DUNCAN ROAD
FREDERICK, MD 21701

DR. 
RUSSELL KENNEL
11150 BENNIE DUNCAN
ROAD
FREDERICK, MD 21701
Phone3013040048   
Fax
Accession Number: CG12-00461

Received: 03/19/2012   Reported: 03/30/2012 
Species: CANINE
Breed: BOXER
Sex: M   Age: 2Y8M
Animal ID: MR. WIGGLESWORTH OPPIE
Case Ref#: 
Specimen: SWB

Results:
GENETIC INFO   ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY (ARVC) IS A FAIRLY COMMON FORM OF HEART DISEASE IN THE BOXER DOG. IT IS INHERITED AND OUR LABORATORY HAS IDENTIFIED A MUTATION RESPONSIBLE FOR THE GENE IN SOME BOXERS. HOWEVER, IT SHOULD BE NOTED THAT IN HUMAN BEINGS WITH THE SAME DISEASE, THERE ARE MANY DIFFERENT GENETIC MUTATIONS WHICH CAN CAUSE THIS DISEASE. WE DO NOT YET KNOW IF THIS IS THE ONLY MUTATION IN THE BOXER OR IF THERE WILL BE MANY DIFFERENT MUTATIONS. PLEASE KEEP IN MIND THAT WE ARE CONTINUALLY LEARNING ABOUT THIS DISEASE AND RECOMMENDATIONS WILL BE ALTERED AS WE OBTAIN MORE INFORMATION. 
CURRENTLY OUR INTERPRETATION OF THE TEST IS: 
NEGATIVE RESULTS: 
THE ABSENCE OF THE MUTATION IN THIS DOG, DOES NOT MEAN THAT IT WILL NEVER DEVELOP THE DISEASE. IT MEANS THAT IT DOES NOT HAVE THE ONLY KNOWN MUTATION THAT CAN CAUSE THE DISEASE IN THE DOG AT THIS TIME. 
POSITIVE RESULTS: 
DOGS THAT ARE POSITIVE FOR THE TEST WILL NOT NECESSARILY DEVELOP SIGNIFICANT HEART DISEASE AND DIE FROM THE DISEASE. SOME DOGS WILL DEVELOP A VERY MILD FORM OF THE DISEASE AND WILL LIVE QUITE COMFORTABLY, SOME MAY NEED TREATMENT. 
IMPORTANTLY, BREEDING DECISIONS SHOULD BE MADE CAREFULLY. AT THIS TIME WE HAVE DO NOT YET KNOW WHAT PERCENTAGE OF BOXERS WILL BE POSITIVE FOR THE MUTATION. HOWEVER, REMOVAL OF A SIGNIFICANT NUMBER OF DOGS FROM THE BREEDING POPULATION COULD BE VERY BAD FOR THE BOXER DOG BREED. REMEMBER THAT DOGS THAT CARRY THIS MUTATION ALSO CARRY OTHER IMPORTANT GOOD GENES THAT WE DO NOT WANT TO LOSE FROM THE BREED.
BOXER ARVC   Negative

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